{"id":4847,"date":"2014-04-01T11:33:31","date_gmt":"2014-04-01T09:33:31","guid":{"rendered":"https:\/\/www.lillegrandpalais.com\/parkinson-developper-la-recherche\/"},"modified":"2014-04-01T11:33:31","modified_gmt":"2014-04-01T09:33:31","slug":"parkinson-developper-la-recherche","status":"publish","type":"post","link":"https:\/\/www.lillegrandpalais.com\/leblog\/au-coeur-de-levenement\/parkinson-developper-la-recherche\/","title":{"rendered":"Parkinson : d\u00e9velopper la recherche"},"content":{"rendered":"<p style=\"text-align: center\"><a href=\"https:\/\/www.lillegrandpalais.com\/wp-content\/uploads\/2014\/03\/defebvrenetb.jpg\"><img decoding=\"async\" class=\"aligncenter  wp-image-12472 lazyload\" title=\"defebvrenetb\" data-src=\"https:\/\/www.lillegrandpalais.com\/wp-content\/uploads\/2014\/03\/defebvrenetb.jpg\" alt=\"\" width=\"421\" height=\"496\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 421px; --smush-placeholder-aspect-ratio: 421\/496;\" \/><\/a><\/p>\n<p style=\"text-align: center\"><strong>Lille Grand Palais avec le parrainage de M comme Mutuelle organise une soir\u00e9e sant\u00e9 \u00ab\u00a0<a href=\"https:\/\/www.lillegrandpalais.com\/leblog\/parkinson-les-traitements-de-demain\/\">Parkinson, les traitements de demain<\/a> \u00bb le 8 Avril 2014. ?Rencontre avec Luc Defebvre, Professeur de Neurologie au service de Neurologie et Pathologie du Mouvement, et au P\u00f4le de Neurosciences et de l\u2019Appareil Locomoteur du CHRU de Lille, qui interviendra lors de la conf\u00e9rence.<\/strong><\/p>\n<p style=\"text-align: center\"><strong>Quel est votre parcours\u00a0?<\/strong><br \/>\nJe suis neurologue dans le service de neurologie et pathologie du mouvement depuis 1992. Je consacre mon activit\u00e9 clinique et de <strong>recherche<\/strong> dans le domaine de la maladie de Parkinson et des syndromes parkinsoniens apparent\u00e9s. Pour les activit\u00e9s de recherche, mon implication concerne plus sp\u00e9cifiquement le domaine de l\u2019\u00e9lectrophysiologie ainsi que l\u2019\u00e9tude de la locomotion et des troubles cognitifs dans la maladie de Parkinson. Nous avons \u00e9galement d\u00e9velopp\u00e9, en collaboration avec l\u2019\u00e9quipe de neurochirurgie fonctionnelle du Professeur Blond, les techniques de <strong>stimulation c\u00e9r\u00e9brale profonde<\/strong>. Nous participons \u00e9galement activement aux diff\u00e9rents protocoles de recherche nationaux, mais \u00e9galement aux protocoles th\u00e9rapeutiques qui ont pour but de tester de nouvelles mol\u00e9cules dans cette pathologie.<\/p>\n<p style=\"text-align: center\"><strong>Quel est votre r\u00f4le aupr\u00e8s des malades au sein du service de neurologie et pathologie du mouvement\u00a0?<\/strong><br \/>\nNous assurons, en <strong>collaboration<\/strong> avec l\u2019\u00e9quipe m\u00e9dicale et param\u00e9dicale, la prise en charge des patients parkinsoniens aux diff\u00e9rents stades de la maladie\u00a0: au stade initial pour confirmer le <strong>diagnostic<\/strong>, entourer le patient et sa famille au moment de l\u2019annonce en lien avec les neuropsychologues du service, mais aussi un stade plus \u00e9volu\u00e9 quand les sympt\u00f4mes \u00e9voluent et que d\u2019autres traitements doivent \u00eatre envisag\u00e9s dans le cadre de techniques de stimulation. Nous assurons cette prise en charge aupr\u00e8s des patients soit par le biais de l\u2019hospitalisation dans notre service, soit par des consultations externes. La <strong>prise en charge<\/strong> des patients est \u00e9galement assur\u00e9e en \u00e9troite collaboration avec les neurologues lib\u00e9raux et les neurologues des h\u00f4pitaux g\u00e9n\u00e9raux de la r\u00e9gion Nord-Pas-de-Calais. Une collaboration active avec d\u2019autres services du CHR de Lille est \u00e9galement assur\u00e9e, notamment les services de neurochirurgie fonctionnelle (Professeur Blond), de r\u00e9\u00e9ducation (Docteur Blanchard), d\u2019imagerie morphologique et fonctionnelle, de neurophysiologie clinique, et enfin de psychiatrie.<\/p>\n<p style=\"text-align: center\"><strong>Est-il possible de retarder l\u2019\u00e9volution de la maladie\u00a0? Si oui, comment\u00a0?<\/strong><br \/>\nActuellement la prise en charge th\u00e9rapeutique de la maladie de Parkinson repose sur des traitements symptomatiques qui ont pour but de compenser la perte de dopamine au sein du cerveau des malades. Il ne s\u2019agit donc pas d\u2019un traitement de la cause de la maladie qui n\u2019est pas encore d\u00e9finitivement connue. L\u2019association de ces diff\u00e9rents traitements et de la prise en charge assur\u00e9e par les m\u00e9decins et les \u00e9quipes soignantes permet dans un bon nombre de cas d\u2019<strong>att\u00e9nuer les sympt\u00f4mes<\/strong>. Des \u00e9tudes sont men\u00e9es pour mieux comprendre la cascade des \u00e9v\u00e9nements cellulaires et mol\u00e9culaires qui entra\u00eenent la perte des cellules dopaminergiques au sein du cerveau. Des techniques de <strong>neuroprotection<\/strong> permettront nous l\u2019esp\u00e9rons \u00e0 terme de d\u00e9velopper des mol\u00e9cules afin de <strong>pr\u00e9venir la d\u00e9g\u00e9n\u00e9rescence des cellules<\/strong> et d\u2019agir ainsi en amont avant que les sympt\u00f4mes de la maladie ne puissent s\u2019aggraver.<\/p>\n<address>Mardi 8 Avril de 18h30 \u00e0 22h30 \u00e0 Lille Grand Palais<br \/>\nentr\u00e9e gratuite, inscription conseill\u00e9e : www.soiree-sante.com<\/address>\n","protected":false},"excerpt":{"rendered":"<p>Lille Grand Palais avec le parrainage de M comme Mutuelle organise une soir\u00e9e sant\u00e9 \u00ab Parkinson, les traitements de demain \u00bb le 8 Avril 2014. ?Rencontre avec Luc Defebvre, Professeur de Neurologie au service de Neurologie et Pathologie du Mouvement, et au P\u00f4le de Neurosciences et de l\u2019Appareil Locomoteur du CHRU de Lille, qui interviendra lors de la conf\u00e9rence.<\/p>\n","protected":false},"author":1,"featured_media":4848,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[38],"tags":[],"class_list":["post-4847","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-au-coeur-de-levenement"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Parkinson : d\u00e9velopper la recherche<\/title>\n<meta name=\"description\" content=\"Lille Grand Palais organise une soir\u00e9e sant\u00e9 \u00ab Parkinson, les traitements de demain \u00bb le 8 Avril 2014. ?Interview de Luc Defebvre.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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